Less invasive surfactant administration (LISA)

A recent medical technique, known as less invasive surfactant administration (LISA), has been started at J.K. Lon Government Children’s Hospital here for treatment of lung disease or respiratory distress syndrome among premature babies.
The procedure started initially for newborn children with a birth weight of less than 1,500 grams, has yielded encouraging results.
Most of the premature babies admitted to the hospital’s neonatal intensive care unit had the problem of less mature lungs, resulting in difficulty in breathing at the time of birth. They needed ventilatory support with surfactant administration via an endotracheal tube placed in an air pipe for treatment.
The surfactant is administered via a thin feeding tube, instead of the endotracheal tube, which is immediately removed after the procedure, while the baby is on the CPAP machine.
LISA technique had been found to be very helpful in minimising the side effects.
LISA has been developed as a lung protective strategy for respiratory management and ventilation in view of mechanical ventilation causing damage to the preterm lungs of newborns.
Infants considered suitable for LISA are those being managed with primary CPAP or high flow with the evidence of increasing respiratory distress and with a rising oxygen requirement.

Source: TH

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