Chitra GeneLAMP-N

The Chitra GeneLAMP-N was developed by the Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Thiruvananthapuram
The Chitra technology uses a method called Loop-mediated isothermal amplification (LAMP).
The objective, like that of the gold-standard RT-PCR tests, is the same: to detect the presence of viral RNA. Both achieve this via a series of chemical transformations.
The LAMP method is said to be faster but is a relatively newer technology, more complicated in its design and has not been tested extensively for COVID-19 detection.

N gene test

Most RT-PCR kits focus on two different genes, the E (envelope) gene and the RdRP (RNA-dependent RNA polymerase) gene.
The World Health Organization recommends an E and RdRP test, while the U.S. Centers for Disease Control and Prevention (CDC) requires an N gene test.
The N gene test is a confirmatory test and is widely employed in Germany and China, among other countries.
However, the design of it is complicated and can be expensive.
The CDC protocol says three regions of the N gene must be analysed but the Chitra-model tests two to confirm the identity of the virus.

Source: TH

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